James Pickens Jr. is best known for his starring role as Dr. Richard Webber on the television series Grey's Anatomy and for his supporting roles as Deputy Director Alvin Kersh on later seasons of the series The X-Files and Chuck Mitchell on Roseanne (1990–96; 2018) and The Conners (2018–22). In the February 28, 2007 all-star benefit reading of "The Gift of Peace" at UCLA's Freud Playhouse, he portrayed a man whose life experiences led him to volunteer in the peace movement. The play was an open appeal and fundraiser for passage of U.S. House Resolution 808, which sought to establish a Cabinet-level "Department of Peace" in the U.S. government, to be funded by a two-percent diversion of the Pentagon's annual budget. In 2018, Pickens has reprised his role as Chuckie Mitchell in two episodes of the tenth season revival of Roseanne. In 2019, he was inducted into the National Multicultural Western Heritage Museum.